Preventing translocation of deleterious substances using intestinal mucosal epithelium
The intestinal mucosal epithelium plays an important role in preventing translocation of deleterious substances or
organisms present within the lumen of the gut and in preserving normal homeostasis. Impairment of the epithelial
surface barrier may facilitate the penetration of harmful factors from the intestinal lumen, leading to acute and
chronic inflammatory changes caused by the initiation of a complex network of immune responses.