Effect of antisecretory factor on the immune system and the nervous system

  • García Franklin
Keywords: Diarrhoea, Inflammatory bowel disease, endogenous protein, Clostridium difficile


Antisecretory factor is a 41 kDa endogenous protein which was originally purified in the pig pituitary gland and since then its gene has been cloned and sequenced. It has been established that AF is synthesised in most tissues of mammals and can be found linked to the 26S proteasome or free in the cytoplasm and/or nucleus.