Effects of Different Doses of Curcumin Supplementation on Myocardium and Exercise Time of Exercise Rats

  • Weilong Chen
Keywords: Curcumin; Lactate dehydrogenase; Fatigue exercise; Serum creatine kinase

Abstract

Curcumin is a phenolic compound extracted from Curcuma longa, which has a wide range of pharmacological effects due to its good antioxidant and free radical scavenging effects. Curcumin has many pharmacological actions, such as anticancer, arthritis treatment, Alzheimer's disease delay, blood lipid reduction and so on. After high dose of curcumin, the MDA content in the myocardium of rats was significantly lower than that in the exercise control group, and the MDA content in the skeletal muscle of rats with medium and high dose of curcumin was significantly lower than that in the exercise control group (P < 0.05). The results suggest that curcumin may alleviate the injury of rat heart and skeletal muscle by increasing the activity of antioxidant enzymes and decreasing the lipid peroxidation.

Published
2020-02-01